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Global Presence of Indian Herbs

In the middle of a dark, dense forest, one man saw a ray of hope. That great man, Shri Ram Lal Agrawal was inspired by the following thought published in an eminent journal on practical medicine, The Practitioner, in December, 1950..


"The lore of the countryman is built upon the experience of generations, often of centuries, and the data upon which it  is based have often been obtained at a price in human lives which no modern research worker would ever dream  of considering. It is particularly appropriate at the present moment, when the pharmaceutical companies of the world are emitting an unceasing flow of  new synthetic drugs, that attention should be turned to the possible  remedies that may be found among indigenous herbs of this and other countries."



Shri Ram Lal Agrawal was a renowned expert on identification, collection and therapeutic application of herbs. He was fascinated by the virtues of the 5000 year old Indian System of Medicine called Ayurveda, which deals with the use of herbs for the treatment of humans and animals.

Since then Indian Herbs has investigated what our ancestors did 5000 years ago, searched, researched, scientifically developed, pharmacologically tested and clinically evaluated the herbal products on modern scientific lines using the latest technology.

Indian Herbs, Saharanpur (UP), Indian established in 1951 is the leading and pioneer company, manufacturing herbal animal health care products for ruminants, poultry, pigs, equines, pets, aqua and other animal specials for over 50 years.

According to the survey conducted by BioSpectrum and Association of Bio technology led Enterprises (ABLE), The Indian Herbs is the only company from the sector of Herbal Human and Animal Health Care products research and manufacturing in the Top 30 Biotechnology led enterprises of India, well ahead of many Parma companies. Also, according to ORG-an independent market survey organization-Indian Herbs is one of the Top 4 companies in total Animal Health Care Products market in India, successfully competing with multinational companies due to consistent quality and modern scientific research. Most of the Indian Herbs products are brand leaders in their respective therapeutic segments.

India Herbs is the first ISO 9001:2000 certificate company engaged in Research and Manufacturing of Herbal Animal Health Care product (Awarded by Det Norse Veritas, The Netherlands)

Indian Herbs is also engaged in research, development and manufacturing of unique Ayurved Specialities (Human Herbal Medicines particularly for those therapeutic segments where modern system of medicine does not provide satisfactory cures and similarly not much has been offered, so far, by alternative system of medicine. The standardized herbal extracts, developed and manufactured by Indian Herbs are being used in herbal health care formulations, neutraceutivals, cosmetics and dietary supplements etc.

Nature’s way to animal health
The theme “Nature’s Way to Animal Health “ adopted by Indian Herbs gives the true expression to company’s philosophy and symbolises its positioning in the market. The founder, a visionary of his time, envisaged the farmers themselves can use the use of herbal products that can be prescribed by Veterinarians or that, without a veterinary prescription.

Research & Development
Research & Development has been pivotal in the development of INDIAN HERBS. Continuous high level research helped in developing more than 50 successful formulations during the last five decades. More that 145 scientists have been awarded higher degrees such as M.V.Sc, M.SC, M.F.Sc, or PhD for outstanding research studies on these herbal health care products and more than 600 research papers have been published on Indian Herbs products in the eminent national and international scientific journal.

The dynamic team of scientists includes Pharmacists, Chemists, Botanists, Microbiologists, Pharmacology’s, Clinic ions etc., in different departments such as Pharmacology, Formulation, Photochemistry, Microbiology, Quality Control, Literature Survey, Animal House and Veterinary and Medical Services etc.

The level of sophistication and capabilities of the R& D center attained greater heights with the installation of most modern and sophisticated instruments such as :-

HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC) consisting of “Linomat IV” microprocessor controlled TLC sampler and computer controlled HPTLC scanner.

HIGH PRESSURE LIQUID CHROMATOGRAPHY WITH PDAD(HPLC) consisting of ultra modern Rl & photodiode Array Detector coupled with powerful software and sophisticated solvent delivery system.

GAS CHROMATOGRAPHY – MASS SPECTROMETRY with FID,ECD & MASS DETECTORS.

CLIMATIC HUMIDITY CHAMBERS

UV-VIS SCANNING SPECTROPHOTOMETER & SPECTROFLUROMETER etc.

These systems are the best available equipments for standardization and quality control of herbal products.The available facilities of Atomic Absorption Spectrophotometer, Gas Chromatograph and other equipments are being utilized very efficiently.

Department of Indian System of Medicine and Homeopathy, Ministry of Health, Govt. of Indian has accorded accreditation to us for research on Ayurveda and other Indian System of Medicine.

Recognition of R& D Centre
In realization of the achievements of our R&D center, the Ministry of Science and Technology, Government of India has granted to it the recognition and formal certification – the first of its kind in Indian.

Worldwide Research
Extensive researches including experimental studies and clinical evaluations have been successfully accomplished in many countries all around the globe. The clinical trials have been conducted at farms, feed mills, breeding centers, and allied research institutions in different countries. The results of these studies are published in international journals.

Standardization and Quality Control
Quality is never an accident. It is always the result of high intention, since effort, intelligent direction and skilful execution”. John Ruskin.

Relentless pursuit of this dictum has ensured the quality of our products.

Quality Control of Herbal ingredients
An essential factor in the assembly of any herbal product is the availability of quantitatively standardized herbal ingredients. The complex nature of the components and active ingredients mixed with helper or synergistic compounds without an active role make actual identification of the active ingredients difficult. This does not , however preclude scientific standardization of any particular preparation.

An outline of Quality Control Techniques employed by us is given below: -

Identification and Authenticity of Plant Material
All herbal ingredients meet the quality control standards, set for each particular ingredient. Our scientists select the best herbal materials from chosen location at right altitudes with proper soil and environmental conditions, harvest at the optimum time and ensure the correct post harvest treatment and storage.

Our Quality Assurance Laboratory preserves and maintains a specimen and Data Base containing full information on each plant material, used by INDIAN HERBS. Every herbal ingredient is authenticated by experts, involving both macroscopic and microscopic examination of each plant material,.

Quality Through Cultivation
Our R&D has developed cultivation packages for remunerative farming of herbs containing optimum quantity of desired active constituents. These methods are applied of INDIAN HERBS farms and our experts also educate and train the farmers about the cultivation of such herbs with buy-back guarantee arrangements to ensure regular availability of right quality herbal ingredients.

CHEMICAL TESTS

Besides physical tests many other parameters are used to standardize and evaluate the quality of the herbal materials.

  • Moisture

The moisture content of any herbal ingredient is important since it must be minimal for proper storage and processing,

  • Total Ether Extract.

This quantifies the terpenoids and other volatile & fixed oils in the herb.

Water Alcohol Soluble Extracts
Water and alcohol extractive values broadly represent the net quantitative values of the active constituents e.g. alkaloids, glycosides, flavanoids, polysaccharides, amino acids etc., in the herbal material.

 

  • Ash Value

This evaluates the mineral content of the sample and presence of foreign inorganic material, if any.

Standardization of Herbal Products.
Unlike synthetic drugs, the active principles in the plant are not always clearly defined and often they are a complex mixture of several closely related constituents e.g. glycosides, alkaloids, terpenoids, flavonoids, amino-acids etc.

Herbal product standardization can be achieved by finger prointing, using chromatographic techniques. Computer controlled high performance chromatographic techniques provide a complete system of qualitative and quantities evaluation of plant constituents.

The raw herb of finished product is extracted with difference organic solvents, which are applied to the HPTLC/HPLC plate in microgram quantities, and chromatogram is then developed using different solvent system, which separate the components of the sample under investigations. The chromatogram thus developed is scanned using a computer controlled viewing system that records and quantities the individual components of any mixture.

The report shows the TLC picture along with the areas of each peak. The unique spectra of any peak may be used to confirm the identity of any particular compound. Like the thumb-print of two individual can never be identical, so it is for finger print chromatogram of any plants constituent. It is this that forms the basis of standardization of herbal raw materials and poly herbal mixtures.

Quality Control of Finished Products

Finished products are subjected to strict quality control tests, which involve:

  • Physico-chemical analysis
  • HPTLC/HPLC finger printing
  • Pharmacological evaluation and clinical trials.

The chromatogram developed for each manufactured batch is compared with the standard reference chromatogram to ensure batch consistency and reproducibility for uniform results ensuing the quality of the finished product.

Good Manufacturing Practices
Manufacturing located at Saharanpur (U.P), close to Himalayas, in the lap of Shivalik range, which is repository of herbs rich in medicinal values, they are well equipped with the state-of-the art equipments manned by highly qualified and trained technologists and backed by a refined manufacturing culture.

Packing of finished products is done using modern automated system. The machines weigh or count, fill and se seal the packs on line. The end product is therefore untouched by human hands. The automation of the entire process effectively meet the requirements of “Good Manufacturing Practices “(GMP), as per the guidelines of W.H.O Indian Herbs is first to get GMP Certificate for manufacturing of Ayurvedic Human and Animal Health Care Products from the Govt.

Animal and Products
The products at Indian Herbs have been developed for different animal sectors such as RUMINANTS,PIGS, POULTRY, EQUNIES, CANINES, FELINES, AQUA and other animal species.

Suitable for “Organic Farming”
The Society for Control and Certification of Quality Assurance, Koeln, Germany, an authorized EEC agency for quality control, evaluated many of our herbal products and found that these herbal feed supplements are suitable for ecological and organic farming as per the requirements of the existing and planned regulations (EEC, 2092/91).

Patents
Indian Herbs has the distinction of getting more than 22 patents in US, Europe, Australia etc and many of patents are pending in US and other countries for innovative research on its herbal products. Indian Herbs has also developed and patented a unique drug delivery system for medicines and nutritional supplements.

Indian Herbs-Global Success
INDIAN HERBS products have been registered or authorised for marketing in many countries such as UK, Germany, Austria, Denmark, Switzerland, Spain, Cyprus, Italy, Portugal, Ireland, Czech Republic, South Africa, Korea, Malaysia, Thailand, Taiwan, Bangladesh, Pakistan, Srilanka, Philippines, Nepal, Bhutan etc. In many other countries these products are under active consideration of respective authorities for granting registration/ approval for marketing.

International Marketing Network
INDIAN HERBS INTERNATIONAL is established as a separate and independent division to promote the export of these products to world markets. The above world map shows the countries where marketing networks have been established for Indian Herbs Products.

Responding to Emerging Global Needs
To summarise, we sow the seeds of quality in nature-monitor the progression-reap the harvest of efficiency and provide satisfaction to the customer in terms of efficacy, freedom from toxicity and cost effectiveness. The result is that INDIAN HERBS sets the standards of quality, safety and efficacy for herbal products that others only struggle to achieve.

All over the world there is growing interest in alternative (natural) medicines and feed supplements. It is increasingly felt that future will belong to medicines and health food based on natural products. We are fully equipped to meet these requirements.

We look forward to your valuable suggestions, support and patronage.

 

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